研究室: 資505B

經歷

國立高雄科技大學 助理教授 (Aug. 2023 – until now)

高雄科技大學  博士級研究員(Feb. 2021 – Jul. 2023)

高雄醫學大學  博士級研究員  (Feb. 2015 – Jan. 2021)

國立成功大學 博士級研究員  (Mar. 2014 – Dec. 2014)

南亞科技股份有限公司   蝕刻製程工程師 (Mar. 2007 – Dec. 2008)

申豐特用應材股份有限公司  研發處研究員 (Sep. 2005– Feb. 2007)

產學合作或技轉共2件:
1. 申豐化學工業股份有限公司；業界科專計畫“全交聯有機奈米橡膠微粒開發計畫”94-EC-17-A-01-11-0002。    
2. 聚合國際股份有限公司；技術授權”金奈米(rod-in-shell、球)與上轉換材料的製備技術”。

專利:
1. 奈米結構、其應用裝置及其製備方法；台灣-201433540
2. 於不改變形貌下將低還原電位金屬轉換成高還原電位金屬之方法; 台灣- I476282
3. Nanostructure, applied device and preparation method thereof; EUROPEAN-13177533.0
4. Nanostructure, applied device and preparation method thereof; United States-13/947,360
5. Method for transferring a metal with a relative low reduction potential into; United States-13/921,740

研究興趣

1. 半導體奈米感測材料 (Semiconductor sensing nanomaterials)
2. MEMS感測元件 (MEMS sensing device)
3. 三維半導體封裝技術 (Semiconductor 3D packaging technology)
4. 奈米磁電/壓電/摩擦電發電機 (Nano-magnetic/piezoelectric/triboelectric generators)
5. 生醫光電技術 (Biomedical Optoelectronics Technology)
6. 半導體量測技術 (Semiconductor Measurement Technology)
7. 氫燃料電池 (Hydrogen fuel cell)
8. 奈米材料量子物理模擬 (Quantum physics simulation of nanomaterials)

期刊論文

1. 1. Tsai, M. F., Wang Y. M., and Hsueh, T. J.*, "Sulfur-Doped Tin Dioxide deposited by co-sputtering applied to the Hydrogen gas sensor". (Manuscript under preparing)
   2. Tsai, M. F., Zheng, H. Y., and Hsueh, T. J.*, "Silicon Nitride/Tin Oxide Employed Hydrogen Sulfide Gas Sensor for Long Periods in the Industrial Field". Sensors and Actuators: B. (Manuscript under review)
   3. Liang, J. N., Nargotra, P., Tsai, M. F., Wang, H. M. (David), Chen, C. W., Chiu, C. C., Liu, Y. C., Kuo, C. H., "pH-responsiveness and environmental stability of chondroitin sulfate and chitosan nanocapsules encapsulating fish oil" (Manuscript under review: CARBPOL-D-25-07664)
   4. Tsai, M. F., Wu, C. L., and Hsueh, T. J.* “Tin-Doped Gallium Oxide MEMS structure Hydrogen Sulfide gas sensor developed by co-sputtering method”. Journal of Alloys and Compounds. (Manuscript under review)
   5. Chen, S. Y., Shu, E. D., Huang, J. J., Chen, Y. C., Hsu, S. K., Chang, W. T., Lin, I. L., Kuo, C. H., Tsai, M. F., Wen, Z. H.*, Chiu, C. C., "Diphenyl Disulfide Exerts Dual Cytotoxic Effects by Inducing Ferroptosis and Apoptosis in Melanoma Cells", Arch Immunol Ther Exp (2026) 74:000
   6. Tsai, M. F., Fan, S. H., and Hsueh, T. J.* “Manufacture of a stable MEMS Gas Sensor using Radio-frequency Sputtering Deposition and the Hyperthermal Annealing of GaOx/CuInGaSe2 Films”. Sensors and Actuators: B. Chemical, 442 (2025) 138130. (SCI, IF: 7.7/ Chemistry, Analytical/ Ranking: 6/111=5.4%, (Q1))
   7. Tsai, M. F., Ding, R.Y., and Hsueh, T. J.* “Optimized Gallium Oxide/MEMS Gas Sensor for H₂S Gas Detection that exhibits increased Sensitivity and Stability”. Applied Surface Science, 696 (2025) 162944. (SCI, IF: 6.9/ Materials science, Coatings & films/ Ranking: 3/23=13%, (Q1))
   8. Tsai, M. F., Liao, W. C., and Hsueh, T. J.* “Comparative Study of the sensitivity of H2S and NO2 in CuInSe 2 Gas Sensors that are Fabricated using Screen Printing and MEMS Integration”. Applied Surface Science, 676 (2024) 160995. (SCI, IF: 6.9/ Materials science, Coatings & films/ Ranking: 3/23=13%, (Q1))
   9. Tsai, M. F.,^# Nargotra, P.,^# Liao, K. T., Wang, H. M. D., Liu Y. C., Tsai, Y. H., and Kuo, C. H.,*, “High Oxidative Stability of a Complex Fish liver oil Nano-capsule Against Longterm Storage, Hyperthermal, and Sunlight Exposure”. J. Sci. Food and Agric., 2024, 104(6):3594-3605. (#Equal contribution, SCI, IF: 4.1/ Agriculture, multidisciplinary/ Ranking: 11/58, (Q1))
   10. Tsai, M. F., Huang, C. Y., Nargotra, P., Tang, W. R., Liao, K. T., Lee, Y. C., Lin, C. M., Lin, C., Shieh. C. J., and Kuo, C. H.,* “Green extraction and purification of chondroitin sulfate from jumbo squid cartilage by a novel procedure combined with enzyme, ultrasound and hollow fiber dialysis”, J. Food Sci. Technol. 2023, 60(6),1711. (SCI, IF: 3.1, Ranking: 69/142, Food science & technology, (Q2), Citations: 2)
   11. Guo, L. Z.,^# Wu, C. H.,^# Tsai, M. F.,^# Cheng, F. Y.,^# Vijayakumar, S., Tsai, Z. U., Zhang, Z., Liu, T. M.,* and Yeh, C. S.,* “Plasmon resonant two-photon luminescence inducing photosensitization and nonlinear optical microscopy in vivo by near-infrared excitation of Au nanopeanuts” Applied Sciences, 2021, 11(22), 10875. (#Equal contribution, SCI, IF: 2.679, Ranking: 55/170, Engineering & multidisciplinary, (Q2), Citations: 1)
   12. Yang, K. R.,^# Tsai, M. F.,^# Shieh, C. J., Arakawa, O., Dong, C. D.*, and Kuo, C. H.*, “Ultrasonic-assisted extraction and structural characterizeation of chondroitin sulfate derived from jumbo squid cartilage”. Foods, 2021, 10, 2363. (SCI, IF: 4.35, Ranking: 37/163, Food science & technology, (Q1), Citations: 16)
   13. Sivasoorian, S. S., Dahms, H. U., Tsai, M. F., Lo, Y. L., Wang, L. F.*, ”Comparative study of an antimicrobial and a neuropeptide conjugated with gold nanorods for targeted photothermal killing of bacteria”. Colloids and Surfaces B: Biointerfaces. 2021, 208, 112117. (SCI, IF: 5.268, Ranking: 11/71, Biophysics, (Q1), Citations: 7)
   14. Tsai M. F.,^# Chang, P. K.,^# Huang, C. Y., Lee, C. L., Lin, C., Shieh, C. J., Kuo, C. H.*, “Chitosan-based anti-oxidation delivery nano-platform: Applications in encapsulation of DHA-enriched fish oil”. Mar. Drugs. 2021, 19, 470. (SCI, IF: 5.118, Ranking: 12/63, Pharmacology & pharmacy, (Q1), Citations: 8)
   15. Tsai, M. F.,^# Lo, Y. L.,^# Soorni, Y., Sivasoorian, S. S., Yang J.Y., Su, C. H., and Wang, L. F.*, “Near-Infrared Light-Triggered Drug Release from UV- and Redox-Responsive Polymersome Encapsulated with Core-Shell Upconversion Nanoparticles for Cancer Therapy”. ACS Appl. Bio Mater. 2021, 4, 4, 3264–3275. (SCI, IF: 3.25, Ranking: (Q1), Citations: 28)
   16. Chirra, S., Wang, L. F., Aggarwal, H., Tsai, M. F., Soorian, S. S., Suresh, S., Goskula, S., Gujjula, S. R.*, and Venkatathri, N.*, “Rapid synthesis of a novel nano-crystalline mesoporous faujasite type metal-organic framework, ZIF-8 catalyst, its detailed characterization, and NaBH₄ assisted, enhanced catalytic Rhodamine B degradation”. Materials Today Communi., 2021, 26, 101993. (SCI, IF: 2.678, Ranking: 151/314, Materials science, multidisciplinary, (Q2), Citations: 23)
   17. Tsai, M. F.,^# Lo, Y. L.,^# Huang, Y. C., Yu, C. C., Liao, Z. X., Wu, Y. T., Chen, Y. J., Su, C. H., and Wang, L. F., “Multi-stimuli-responsive DOX release from magnetosome for tumor synergistic theranostics”. International Journal of Nanomedicine, 2021, 15, 8623-8639. (SCI, IF: 5.115, Ranking: 28/276, Pharmacology & pharmacy, (Q1), Citations: 10).
   18. Tsai, M. F.,^# Lo, Y. L.,^# Soorni, Y., Hsu, C., Liao, Z. X., and Wang, L. F.*, “Dual stimuli-responsive block copolymers with adjacent Redox-and Photo-cleavable linkages for smart drug delivery”, Biomacromolecules, 2020, 21, 3342 − 3352. (Equal contribution, SCI, IF: 6.988, Ranking: 5/90, Polymer science, (Q1), Citations: 18)
   19. Tsai, M. F., Hsu, C., Yeh, C. S., Hsiao, Y. J., Su, C. H.*, and Wang, L. F.*, “Tuning the Distance of Rattle-Shaped IONP@Shell-in-Shell Nanoparticles for Magnetically-Targeted Photothermal Therapy in the Second Near-Infrared Window”, ACS Appl. Mater. Interfaces, 2018, 10 (2), pp 1508–1519. (SCI, IF: 8.456, Ranking: 27/293, Materials science, multidisciplinary, (Q1), Citations: 36)
   20. Sung, Y. M., Lai, Y. C., Tsai, M. F., Hsieh, H. H., Yang, M. H., Wei, P. P., Yeh, C. S., Hsu, F. C., and Chen, Y. F.*, “Broad band plasmonic nanomaterials for high performance solar cells“, J. Mater. Chem. C, 2016, 4, 513-520. (SCI, IF: 5.256, Ranking: 18/148, Physics, applied (Q1), Citations: 17)
   21. Tsai, M. F., Chang, S. H., Cheng, F. Y., Vijayakumar, S., Cheng, Y. S., Su, C. H., Yeh, C. S.*, “Au Nanorod Design as Light-Absorber in the First and Second Biological Near-Infrared Windows for In Vivo Photothermal Therapy”, Acs Nano, 2013, 7, 5330–5342. (SCI, IF: 12. 881, Ranking: 9/251, Materials science, multidisciplinary, (Q1), Citations: 414)
   22. Chien, Y. H.,^# Tsai, M. F.,^# Vijayakumar, S., Sardar, K., Huang, C. L., Yeh, C. S.,*"Escape from the destruction of the galvanic replacement reaction for solid → hollow → solid conversion process in one pot reaction”, Nanoscale, 2013, 5, 3863-3871. (SCI, IF: 6.895, Ranking: 19/241, Chemistry, multidisciplinary, (Q1), Citations: 12)
   23. Tsai, M. F.,^# Tsai, H. Y., Peng, Y. S., Lu, S. C., Chen, J. S., Wang, L. F.*, ”Characterization of hydrogels prepared from copolymerization of the different degrees of methacrylate-grafted chondroitin sulfate macromers and acrylic acid”, J. Biomedical Materials Research A, 2008, 84A, 727–739. (SCI, IF: 3.525, Ranking: 13/52, Materials science, biomaterials (Q2), Citations: 10)
   24. Tsai, M. F.,^# Chiang, Y. L., Huang, G. W., Wu, P. C., Wang, L. F.*, " Oral sustained delivery of diclofenac sodium using calcium chondroitin sulfate matrix", J. Biomater. Sci. Polymer, 2005, 10, 1319-1331. (SCI, IF: 2.690, Ranking: 25/77, Polymer science, (Q2), Citations: 14)

研討會論文

1. Tsai, M. F., Wang, L. F., Annual Meeting of the Polymer Society (AMPS), January 15th, 2005, Hsinchu, Taiwan.

2. Tsai, M. F., Cheng, F. Y., Hu, K. W. and Yeh, C. S., “Ag nanoframes: hollowing Ag prisms through ripening and etching “, 10th Asian Chemical Congress (10 ACC), September 5th, 2011, Bangkok, Thailand.

3. Tsai, M. F., Yeh, C. S., “Targeted delivery of photo-caged Methotrexate (MTX) using truncated octehedra shaped Fe3O4 superparamagnetic nanoparticle”, Collaborative Conference on Materials Research (CCMR), June 25th, 2012, Seoul, South Korea.

4. Tsai, M. F., Yeh, C. S., “Plasmon resonant two-photon luminescence inducing photosensitization and nonlinear biological in vitro and in vivo imaging by near-infrared excitation of Au nanopeanuts “, Annual Meeting of Chinese Chemical Society, December 1st, 2012, Tainan, Taiwan.

5. Tsai, M. F., Yeh, C. S., “Au Nanorod Design as Light-Absorber in the First and Second Biological Near-Infrared Windows for in Vivo Photothermal Therapy “, Sixth International Conference on Advanced Materials and Nanotechnology (AMN6) , February 10th 2013, Auckland, New Zealand.

6. Tsai, M. F., Wang, L. F., “Tuning the Distance of Rattle-Shaped IONP@Shell-in-Shell Nanoparticles for Magnetically-Targeted Photothermal Therapy in the Second Near-Infrared Window (publish version) “, Annual Meeting of Chinese Chemical Society, December 8th 2018, Kaohsiung, Taiwan.

7. Tsai, M. F., Wang, L. F., “The Optical and Magnetic Property of Nanomaterials Apply in Hyperthermia Therapy “, 2018 Annual

meeting of Biomaterials and Controlled Release Society in Taiwan, March 23th 2018, Kaohsiung, Taiwan.

8. Tsai, M. F., Wang, L. F., “The Optical and Magnetic Property of Nanomaterials Apply in Hyperthermia Therapy “, 4th International Congress on Biomaterials & Biosensors (BIOMATSEN 2019), May 12th, 2019, Mugla, Turkey.

9. Tsai, M. F., Wang, L. F., IONPs@ Au/Ag Core-Shell Constructs for Magnetically-Targeted Photothermal Therapy. 2019 Cancer Nanotechnology Gordon Research Conference, June, 2019, VT United States.

10. Tsai, M. F., Wu, Y. T., Wang, L. F., The rattle structure of IONPs@Au/Ag core-shell constructs for magnetically-targeted photothermal therapy. 2019, The 20th International Sol-Gel Conference, St. Petersburg, Russia.

11. Tsai, M. F., Jhang, P. K., and Kuo, C. H.* "Formation of chitosan nanoparticles to encapsulate cobia liver oil" 2021, the 26th BEST Conference & International Symposium on Biotechnology and Bioengineering, July, 2021, Taichung, Taiwan.

   12. Tsai, M. F., Liao, K. T., and Kuo, C. H.* " Ultrasonic assisted extraction of chondroitin sulfate from Dosidicus gigas cartilage by using enzyme method " TSCRE-2021, The 39th Taiwan Symposium on Catalysis and Reaction Engineering, June, 2021, Tainan, Taiwan.

  13. Tsai, M. F., Jhang, P. K., and Kuo, C. H.* " An anti-oxidation nanoplatform construction: the chitosan applications in encapsulation of DHA/EPA enriched cobia liver oil " 2021 TwIChE, January, 2022, Kaohsiung, Taiwan.

  14.  Liao K.T., Tsai M.F., Kuo C.H.*. 2022. Chondroitin sulfate ionic gelation with chitosan encapsulate cobia liver oil to formulate a novel complex nutrition nano-capsule. 27th BEST Conference & International Symposium on Biotechnology. Taoyuan.

  15.  Tsai M.F., Kuo C.H.*. 2022. Ultrasonic-assisted enzymatic method and hollow fiber dialyzer for chondroitin sulfate extraction and purification from jumbo squid cartilage. 10th International Conference on Bioprocesses (IBA-IFIBiop 2022). Kaohsiung.

  16. Tsai M.F., Liao K.T., Kuo C.H.*. 2022. A novel complex nanocapsule containing chondroitin sulfate and chitosan used for encapsulating fish oil. 10th International Conference on Bioprocesses (IBA-IFIBiop 2022). Kaohsiung.

  17. Tang W.R., Zhang J.R., Yang K.R., Liao K.T., Tsai M.F., Kuo C.H.*. 2023. A green process using enzyme, ultrasound, and ultrafiltration for extraction and purification of chondroitin sulfate from jumbo squid cartilage. The 75th Annual Meeting of the Society Biotechnology, Japan. Nagoya, Japan.

  18. Liao K.T., Tsai M.F., Kuo C.H.* 2023. A novel complex nanocapsule prepared by ionic gelation of chondroitin sulfate and chitosan used for encapsulation of fish oil. 2023 Asian Congress on Biotechnology, Ho Chi Minh City, Vietnam.

  19. Liang J.N., Tsai, M. F., Nargotra P., Kuo C.H.* 2024. Preparation and bioenvironmental stability analysis of chondroitin sulfate and chitosan nanocapsules for encapsulation of fish oil. 29th BEST conference. Penghu.

             20. Liang J.N., Tsai, M. F., Nargotra P., Kuo C.H.* 2024. pH-responsiveness and stability of chondroitin sulfate and chitosan nanocapsules encapsulating with fish oil. 29th                  YABEC. Busan, Korea.

   博士論文：奈米金屬材料之合成與生醫治療應用

       碩士論文：不同接枝率的硫酸化軟骨素-甲基丙烯酸酯與丙烯酸交聯聚合水膠之製 備及其物性與形態分析